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  Syringe and multidose vial
  using an ampoule
  using a multidose vial


Self-administration of medication using a multidose vial

Please note that these instructions are for guidance only. Speak to your doctor or fertility specialist for full directions on self-administration.


Mixing (or reconstituting) a multidose vial

  • Wash your hands thoroughly.
  • Place materials on a dry, clean surface.
  • Remove the protective cap from the vial.
  • Carefully twist the cap off the pre-filled syringe of sterilised water.
    • To prevent contamination, avoid touching the needle. 

  • Position the needle of the pre-filled syringe in a straight, upright position over the marked centre circle of the rubber stopper on the vial of powder.
    • Make sure the needle remains in a straight, upright position as you insert it through the centre circle, or it may be difficult to depress the plunger. 

  • Slowly inject the water into the vial by pressing down on the plunger. 
  • When all the water has been injected into the vial, withdraw the needle and dispose of it immediately in your sharps container.
  • Do not shake the vial. 
    • If bubbles appear, wait a few moments for the bubbles to settle. 

Preparing your dose

  • Your fertility team will tell you exactly how much of the medication you are to inject on each day of treatment
  • Wipe the rubber stopper of the vial with an alcohol swab.
  • Remove the outer wrapping from the syringe. 
  • Carefully pull the cap from the needle, avoiding touching the needle. 
  • Firmly holding the vial of reconstituted medication on a flat surface, insert the needle through the marked centre of the rubber stopper.
  • Keeping the needle in the bottle, lift the bottle and turn it upside down with the needle pointing towards the ceiling. 
  • With the needle tip in the liquid, slowly pull back the plunger until the syringe fills to slightly more than the mark for your prescribed dose.
  • Next, keeping the needle in the vial, slowly push the plunger to your prescribed dose.
    • This will clear away any air bubbles. 

  • Remove the syringe from the vial.
    • Recap the needle while you prepare your injection site.    



Injecting your dose

  • Your doctor or nurse will have advised you where to inject (abdomen, thigh or upper arm). 
  • Swab the injection site with alcohol and allow it to dry.
  • Carefully pull the needle cap from the syringe. 
  • Holding the syringe in one hand, hold the skin around the injection site the way you were instructed.
  • Insert the needle at a slight angle.
  • Press down on the plunger in a slow, steady motion until all the medication is injected. 
  • Withdraw the needle and dispose of it in your sharps container.
  • If any bleeding occurs, apply gauze to the site with gentle pressure.  


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Last Updated: 5/6/2008

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