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Drug Therapy

Fewer than 5% of infertile men have a hormonal disorder that can be treated with hormone therapy (or drugs). Hormonal imbalances caused by a dysfunction in the mechanism of interaction between the hypothalamus, the pituitary gland and the testes directly affect the development of sperm. In this type of fertility disorder, gonadotropin therapy is highly successful.

Gonadotropins are sometimes chosen to treat unexplained male infertility, as seen in the cases of oligozoospermia (when sperm count is abnormally low) or asthenospermia (when less than 40% of the sperm are motile).

Other types of drug treatment include antibiotics to treat infertility resulting from infections and treatment with bromocriptine when impaired sperm production is due to hyperprolactinemia (increased levels of prolactin hormone in the blood). 
The two most common hormones required in treatment are:
  • Human Chorionic Gonadotropin (hCG)
  • Recombinant Follicle Stimulating Hormone (rFSH)  


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Last Updated: 5/6/2008

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