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Follicle-stimulating Hormone (FSH)
In females, the primary hormone responsible for
the development of follicles in the ovaries is Follicle-stimulating
Hormone (FSH), an essential step in the development of mature eggs
(oocytes), capable of being fertilized.
In males, FSH is vital for the production of healthy sperm
(spermatozoa).
A cause of infertility is low levels or a lack of secretion of
human FSH in either the man or woman.
Typical scenarios where FSH hormone treatments are used
include:
Women: hormones causing a lack of
ovulation
FSH treatment is used as part of ovulation
induction (OI) treatments as a substitute for the low, or lacking,
naturally occurring FSH. Treatment aims to develop one dominant
ovarian follicle, which at ovulation releases one egg.
Fertilization takes place naturally through intercourse or
intrauterine insemination (IUI).
Women: controlled ovarian stimulation
(COS)
COS is undertaken as part of ART programs, such
as in-vitro fertilization (IVF) and embryo transfer (ET), gamete
intrafallopian transfer (GIFT) and intracytoplasmic sperm injection
(ICSI). The aim of COS is to increase the number of eggs available
for retrieval from the ovaries.
Male: infertility caused by severe FSH and LH
deficiency
This is a condition whereby the body fails to
produce the hormones that stimulate sperm production.
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